Research Fellow (Chemistry)
5750 - 11000 SGDNational University of Singapore
Interested applicants are invited to apply directly at the NUS Career Portal. Please note your application will only be processed if you apply via NUS Career Portal.
NUS Career Portal link:
We regret that only shortlisted candidates will be notified.
Job Description
The successful candidate will work with Asst. Prof. WEI Jiangbo on context-dependent crosstalk between epitranscriptome and epigenome under a project on "Exploiting the synthetic lethal interactions between epitranscriptome and epigenome to overcome epigenetic drug resistance in cancers".
The main responsibilities of the position include:
1. Establish the model system to study context-dependent crosstalk between epitranscriptome and epigenome in the lab.
2. Carry out biochemistry and cell biology-related experiments and bioinformatics work for associated omics.
3. Facilitate grant application.
4. Aid and support to junior PhD students in their research projects.
5. Lead a small group of PhD working on RNA modification in gene regulation and inheritance.
6. Report duty to PI.
Qualifications
• The candidate shall obtain PhD or have submitted a PhD thesis, in Biochemistry and Molecular Biology or related disciplines.
Skills:
• Proficient in a wide range of bench techniques relevant to biochemistry, molecular biology, chemical biology, genetics, and cell biology.
• Skills include, but are not limited to: chemical synthesis, nucleic acid extraction and purification, molecular cloning, plasmid preparation, PCR and RT-qPCR, site-directed mutagenesis, restriction enzyme digestion, ligation, gel electrophoresis (agarose and SDS-PAGE), immunoblotting (Western blot), immunoprecipitation, ELISA, cell culture (bacterial, yeast, and mammalian), cell transfection and transduction, CRISPR-Cas9 genome editing, Sanger and next-generation sequencing (NGS) library preparation, immunofluorescence and confocal microscopy, flow cytometry, protein expression and purification, enzyme assays, and spectrophotometric analysis.
• Has extensive experience in model system that suitable to study the context-dependent crosstalk between epitranscriptome and epigenome.
Experience:
• Have published (or at least submitted) peer-reviewed papers as the first author in high-impact journals.
5750 - 11000 SGD
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